Heart Care Services
Clinical Trials

Affton resident Jeannette Mueller went from taking half a dozen cardiac medications to just one and improved her heart’s pumping ability from a dismal 20 percent to more than 65 percent after working with staff in a heart failure clinic.
St. Anthony’s physicians and staff regularly work with patients who opt to participate in clinical trials designed to test the effects of medications, medical devices and care protocols in the treatment of heart disorders and diseases. All clinical trials are overseen by a cardiologist or cardiovascular surgeon, approved by the Institutional Review Board and coordinated by a Clinical Research Coordinator.
Ongoing and Upcoming Clinical Research Trials at St. Anthony’s Medical Center:
CAPTURE 2 Study: A Post-Approval Study of the Acculink Stent
Systems and Accunet Embolic Protection Systems
CAPTURE 2: Carotid RX Acculink/Accunet Post-Approval Trial to
Uncover Unanticipated and Rare Events
This study will follow patients who have an Acculink carotid stent placed, monitoring for any adverse events.
IMProved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE IT)
This study is comparing two types of cholesterol lowering medications in patients who are admitted to the hospital with an acute coronary event. The study is looking at long term outcomes, comparing the frequency of heart related problems in patients taking the two types of cholesterol lowering medications.
TRIDENT-1 Study: This study uses a new medication in patients with known Congestive Heart Failure (CHF) and chronic kidney problems.
This study is looking at how a new medicine may help protect the kidney function in patients who are admitted to the hospital with breathing difficulties due to their CHF.
TRILOGY Study: A Study of a new medication for treating patients with Non-ST or ST Elevation Acute Coronary Syndromes (ACS) who, for various reasons, cannot have intervention performed for the narrowing in their heart arteries.
This study uses a new medication in patients who will be treated medically after a hospital admission for heart related chest pain. The study will track the number of heart-related problems each of the participants has over several years.
AWARE Study: A study for women who have heart disease that cannot be treated with surgery or coronary stent placement.
This study uses a new medication in patients with heart disease who cannot be treated with surgery or coronary stent placement. The new medication will be given and followed to determine if it increases blood flow to the heart muscle in the areas with blockages or small blood vessels.
For information about these and other clinical trials at St. Anthony’s, please contact our Clinical Research Coordinator at 314-525-1697
For information, please call our Health Access Line at 314-ANTHONY (268-4669) or 800-554-9550 or visit our find a physician online.
At St. Anthony's, our vision is to be the area's premier health care organization — and your first choice for health care services.






